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Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR

(Source: Novo Nordisk) In September 2024: Eli Lilly reported positive Phase 3 results for retatrutide, a novel triple GLP-1/GIP/glucagon receptor agonist, demonstrating an average weight loss of 24.2% at 48 weeks in adults with obesity, representing the highest weight loss achieved with any pharmacological agent to date and approaching bariatric surgery efficacy

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