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Yacoubian T, Fang Y-HD, Gerstenecker A, et al

Methionine specifically activates S-adenosylmethionine (SAMe), the universal methyl donor for hundreds of enzymatic reactions including those that regulate fat metabolism and neurotransmitter synthesis

Vitamin B12 is known to support emotional well-being by balancing neurotransmitters and helping to reduce stress and anxiety

Park H-Y, Jung W-S, Kim S-W, Kim J, Lim K

Notably, this effect of rifaximin was based on the modulation of the gut-liver-muscle axis through the suppression of the endogenous LPS overload by maintaining intestinal barrier function, in addition to its ammonia-lowering properties