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373 SIX1, the most extensively studied of the SIX family members, is known to promote tumor invasion, metastasis, and paclitaxel resistance in breast cancer cells
Research has shown these genes can be turned on via cell-signaling pathwaysthe major one being Nrf2
It should be stressed that guidelines do not favor the prescription of one GLP-1 RA over another, although clinicians are advised to select a compound with proven cardiovascular benefit
10.1002/ptr.7454 [DOI] [PubMed] [Google Scholar] 28.Hosseini S, Lee J, Sepulveda RT, Rohdewald P, Watson RR