Studies in cell culture have demonstrated that specific peptide sequences can upregulate procollagen synthesis in dermal fibroblasts, while others influence the activity of matrix metalloproteinases (MMPs) the enzymes responsible for collagen degradation and ECM remodelling
We observed no evidence of dominance effects ( P = 0.80), indicating that the allelic dosage of the T allele contributes to efficacy in an additive manner
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However, in the present study, we did not observe improvement in the results of ovarian stimulation and embryo quality
The doses were administered subcutaneously once weekly
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