GSH is made exclusively in the cytoplasm of cellsthe water-soluble compartment of the cell
In SLE patients, depletion of glutathione has been associated with various immune abnormalities including deregulation of apoptosis, abnormal cytokine and chemokine production and various clinical features
However, more mechanistic studies in vitro and in vivo are required for addressing how the interplay between glutathione and apoptosis may lead to a break intolerance and aggressiveness of lupus disease activity
Later on, I found out, this was 2011 [00:14:00] University of Texas in Austin did a study on the liposome technology product of glirathione
It exerts its effects by directly quenching free radicals
These mechanisms are complementary rather than competitive, with a significant stacking rationale in wound healing and regenerative protocols that require both structural remodeling and cellular recruitment