Key Facts About GLP-1 Receptor Agonists This class of drugs works by enhancing glucose-mediated insulin secretion, which is further enhanced by double or triple-acting agents, as well as glucose-dependent insulinotropic peptide (GIP) receptor agonists
7E), or gastric inhibitory peptide (Fig
Dosing Schedule Administration: Once-weekly injection under the skin (subcutaneous) Final maintenance dose: 2.4 mg weekly Duration: Used long-term alongside diet and exercise Injection Details Use the FlexTouch pre-filled pen Inject into front of upper arm, upper legs, or stomach Can be taken at any time of day, with or without food Same day each week preferred, but can be changed if at least 3 days between doses Common Side Effects Most Common Nausea (feeling sick) Vomiting (being sick) Diarrhea Constipation Stomach pain Headache Feeling weak or tired Common Dizziness Indigestion/upset stomach Burping and gas Stomach bloating Heartburn/reflux Dry mouth Hair loss Injection site reactions Managing Side Effects Start with low dose and gradually increase Drink plenty of fluids to prevent dehydration Side effects often improve over time Consult doctor if side effects are severe or persistent Serious Side Effects (Seek Immediate Medical Attention) Emergency Situations Severe allergic reaction: Breathing problems, swelling of face/throat, fast heartbeat Pancreatitis: Severe, persistent stomach and back pain that doesn't go away Bowel obstruction: Severe constipation with stomach pain, bloating, vomiting Important Safety Information Do NOT Use Wegovy if you: Are allergic to semaglutide or any ingredients Are pregnant or planning pregnancy (stop 2 months before trying to conceive) Are breastfeeding Have Type 1 diabetes Are using other weight loss products Have severe heart failure Storage and Handling Refrigeration: Store at 2C 8C (36F 46F) Room temperature: Can be kept out of fridge for up to 6 weeks below 30C (86F) Protection: Keep in original carton to protect from light Disposal: Discard pen after 6 weeks even if medicine remains Do not freeze or expose to excessive heat This information is for educational purposes only
When administered as a 250 mg rectal suppository, glutathione bypasses the gastrointestinal tract, potentially reducing degradation by stomach acids and enzymes, thus allowing for better absorption
The ingredient formulation also excludes caffeine
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