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The goal is to completely dissolve the lyophilized powder without agitation or degradation of the compound

An additional passive, unsaturable absorption pathway exists that is used when the intraintestinal folate concentrations exceed 10 M 209

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10.1016/j.regpep.2009.11.012 95 TurkovicB.SikiricP.SeiwerthS.MiseS.AnicT.PetekM.et al (2004)

The immunomodulatory effect of the antidepressant sertraline in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis