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The articles discussion of collagen biology and preclinical mechanism relies on this research lane to distinguish cellular and tissue-model findings from broader human therapeutic claims

In general, HSP70 is induced by diversified stimuli such as hypoxia, acidosis, increased muscle temperature, and ischaemia-reperfusion, most of them are by-products of resistance exercise associated with elevated levels of metabolic stress [30, 89]

doi:10.1038/jp.2016.30

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FDA identified no studies administering BPC-157 by the oral, subcutaneous, nasal, or transdermal routes in UC patients