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(2015) found that when p53 was activated by nutlin-3 or exposed to DNA damage stress, the expression of SLC7A11 was reduced

However, hypoxic conditions and high concentrations of reduced GSH in the TME conspicuously compromise the antitumor effect of PDT

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The MHRA guidance on supplying unlicensed medicines is explicit: an unlicensed product may only be supplied to meet the special clinical needs of an individual patient where a licensed equivalent cannot, and the prescriber carries full responsibility

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[10] Because amylin signaling is a different pathway from the incretin (GLP-1) pathway, cagrilintide is attractive as a partner drug: the two mechanisms can be additive