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Jan-Mar 2002;6(1):65-68

Phase 2 monotherapy data reported up to 10.8% body weight reduction at the 4.5 mg dose versus 3.0% with placebo at week 26 [2]

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The circulating level of retinol-binding protein-4 is lower in women than in men [108], but significantly increases in older individuals independent of body fat percentage [109]