& Wells, C
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Over the past year, the clinical and regulatory landscape of GLP-1s has evolved with new indications and approvals expanding their use
For example, alterations in Wnt signalling, alterations in neuronal translation and defects in synaptogenesis or synaptic function during brain development can all affect the formation and activity of neural circuits
These SCFAs stimulate GLP-1 secretion via the gut microbiome and help regulate inflammation, appetite, and blood sugar
3) Diabetes In 2 studies on almost 3,000 people, high TMAO levels were associated with increased rates of type 2 diabetes [17, 18]