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Omega-3 fatty acids (fish oil or algae-based) reduce inflammation and support heart health, which is particularly important since rapid weight loss can stress cardiovascular adaptation

Gastrointestinal Distress Moderate or severe GI distress is another sign of low B12

A typical loading dose is 1,000 mcg (1 mg) administered intramuscularly several times per week (such as every other day or 3 times per week) for a couple of weeks

Sun damage, smoking, and hydration also play a role

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