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One of the possible mechanisms thought to be related to brain overgrowth is the increased blood concentrations of brain-derived neurotrophic factor (BDNF) in newborns who were later diagnosed with ASD (Hazlett et al., 2011

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Abstract book 22

Consequently, all of these factors which determine sperm quality can be compromised (including the mobility of spermatids, as well as their ability to penetrate the wall of a female egg), resulting in decreased fertility in men