Discussion In the present work we have developed a type of proteolytic chimeras (26S-UIDs) that induce degradation by directing targets to the 26S proteasome, using the proteasomal associated factor USP14 as the anchoring site, and evaluated the degradation of two oncologic targets, IMPDH2 and CERT1, as proof-of-concept
Reilly, D
Glutathione is involved in immune function via regulation of
Athletes worldwide should note that WADA prohibition applies regardless of local regulations about availability
suggests that TB-500 may reduce inflammation-linked signaling within cultures of developing brain support cells referred to as oligodendrocyte progenitor cells
Corsi, C., Pollastri, M., Marrapodi, E., Leanza, D., Giordano, S., and D'Iddio, S