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Estos medicamentos actan mediante varios mecanismos fisiolgicos clave: estimulan la secrecin de insulina de manera dependiente de la glucosa, suprimen la liberacin inapropiada de glucagn, retrasan el vaciamiento gstrico y reducen el apetito a nivel del sistema nervioso central

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A study using subdiaphragmatic vagal deafferentation in rats demonstrated that vagal afferents are not necessary for the orexigenic effect of intraperitoneal ghrelin 27

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7B,C), however, HCMV establishes lifelong persistence in patients