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10.1093/ajcn/nqaa177 59 SeligmanJ.NewtonG

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In the SURMOUNT-1 trial, 24-26% of participants experienced nausea at some point during the study, most commonly during dose escalation phases

The mechanism of action is based on the stimulation of the glucagon-like peptide-1 receptor, which enhances insulin secretion, slows gastric emptying, and supports overall metabolic regulation

Another study found that taking glutathione supplements reduced eye pressure in people with normal-tension glaucoma