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Results Absence of promoter proximal NRF2 at NRF2 signature genes To identify critical pathways downstream of NRF2 activation in cancer, we sought to define a core set of genes and other features associated with NRF2-dependent growth across an expansive panel of cancer cell lines

Imaging of changes in copper trafficking and redistribution in a mouse model of Niemann-pick C disease using positron emission tomography

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First of all, it inhibits the enzyme tyrosinase which is responsible for converting tyrosine into melanin hence less melanin is produced

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