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Specifically, it is a fragment representing the active portion of natural GHRH
- Enhances natural skin whitening processes
This effect substantially weakened in the post-S1 blood sample (Treatment Time S1 meal type S2 meal type interaction in the main model: t 50.0 = 2.61, p = 0.012), though BGL was still significantly lower under Ex compared to Vehicle control treatment (post-S1, Treatment: F 1,4.1 = 24.23, p = 0.0073)
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To investigate whether albumin could be engineered to evade L585 cleavage and the resulting reduction in FcRn binding, we constructed a panel of 18 full-length 585-engineered human albumin variants, in which the C-terminal leucine residue was substituted with each of the other naturally occurring amino acids, except for cysteine (Fig
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