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Regionally, North America and Europe currently dominate consumption, driven by established healthcare infrastructure and higher disposable income

Systemic bioavailability for reaching tendons, bone, or CNS via oral route is expected to be very low for an unprotected 15-amino-acid peptide

The physical pressure and chemical inflammation can damage the nerve root itself

[35] It's estimated that about 1 billion people are deficient or insufficient in vitamin D

This represents a precautionary approach rather than a requirement based on proven deficiency risk

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