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Walsh GL, Gokaslan ZL, McCutcheon IE, Mineo MT, Yasko AW, Swisher SG , Schrump DS, Nesbitt JC, Putnam JB Jr, Roth JA

Combination therapy also modestly improves weight, blood pressure, and lipid parameters, with reductions in body weight of approximately 11.5 kg versus SGLT2i alone, though evidence for additive effects on weight loss is inconsistent

GLP-1 meals may also be suitable for people post-bariatric surgery or following a very low calorie diet (VLCD)

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Neither drug is inherently more muscle-protective