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Study designs to investigate causality rigorously Prospective new-user cohort with active comparator + Recruit new semaglutide users and matched new users of a comparator second-line diabetes therapy with lower genital infection confounding (e.g., DPP4 inhibitor), stratified by menopausal status and baseline GSM

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Zepbound's effect on blood sugar is meal-dependent and dose-stable

Metabolic and dietary changes during weight loss can affect sleep

The attempts to develop new antibiotics have been costly and inefficient, as many potential drugs entering clinical trials (9099%) have been unsuccessful [25, 51]