Semaglutide, marketed as Ozempic, Wegovy, and Rybelsus, is a GLP-1 receptor agonist FDA-approved for type 2 diabetes and chronic weight management
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Common sites include the abdomen, glutes, or thighs
In addition, despite previous reports on the capacity of GLP1 on its own to activate the female reproductive axis 67 , this effect was not detected in our study, with no long-term impact on LH or AMH levels, which might suggest a state of refractoriness due to persistent androgenization
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The most common side effects are gastrointestinal, including nausea (up to 44%), diarrhoea (30%), vomiting (24%), and constipation (24%)