glp 1 for psoriasis The potential role of GLP-1 receptor agonists in the management of psoriatic disease: a scoping review Psoriasis Patients Could Benefit From

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37, e257

NEJM Dec 2025) 12 None (no approved label) MTC thyroid C-cell (rodent, human relevance unestablished) 28 None published None published Once weekly, subcutaneous Once weekly, subcutaneous US: late 2027 earliest (NDA Q4 2026 at soonest) 22 Already approved (US: 2022/2023/2024

Sudakov KV, Umriukhin PE, Rayevsky KS

Results Training data We used experimental potency measurements (EC 50 ) at both GCGR and GLP-1R for a total of 125 peptide variants to fit models that relate peptide sequences to in vitro activity against each receptor

IV therapy represents one method of addressing nutritional needs when oral intake proves challenging