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July 1, 2026 If your time is short Retatrutide is a weekly injection being studied as a treatment for obesity, type 2 diabetes, knee osteoarthritis pain, obstructive sleep apnea, chronic low back pain and liver disease

At $79.99 per month for semaglutide microdosing, this is actually one of the more affordable ongoing options from Maximus

Patients inadequately controlled with diet and exercise alone If therapy with a combination tablet containing sitagliptin and metformin is considered appropriate for a patient with type 2 diabetes mellitus inadequately controlled with diet and exercise alone, the recommended starting dose is 50 mg sitagliptin/500 mg metformin hydrochloride twice daily

GLP1s in higher amounts also act on portions of the brain that suppress appetite and signal satiety (feeling full)

Begin at a low dose

Widespread access to GLP-1s for weight loss would be financially unsustainable for many employers