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Dose Escalation Structure Phase Weekly Dose Weeks 14 1 mg Weeks 58 2 mg Weeks 912 4 mg Maintenance (research range) 68 mg Clinical trials have evaluated doses up to 12 mg once weekly with gradual titration

26 Statins were initiated in 380 patients in that study and 159 patients in the 25 mg OCA group, but cardiovascular outcomes were not different between the groups

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The main objective is to deliver an offline RAG model on aerospace content and obtain insights

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