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Whereas non-cystic fibrosis cells upregulate CHAC1 following infection with various pathogens (including Pseudomonas aeruginosa , human coronavirus, cytomegalovirus, tick-borne flaviviruses, Zika virus, and Mycoplasma hominis ), cystic fibrosis cells show an impaired response
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Jung and colleagues introduced a novel microfluidic platform designed to cultivate 3D lung cancer organoids and perform drug sensitivity assays within a single micro-physiological system (161)
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