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Conclusion Even at an advanced disease stage, a two-pronged approach, targeting (a) HGF/c-MET with relevant inhibitors and (b) cancer cells with chemotherapy, completely eliminated metastasis and significantly decreased tumour growth, suggesting that this is a promising treatment approach for PC

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For metabolites, a nominal P 0.05 and FDR 0.05 was considered significant, and a P 0.05 and FDR 0.15 considered marginally significant