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Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system

Berberine activates AMPK indirectly and produces modest metabolic changes, whereas GLP-1 drugs directly stimulate potent receptor signaling with measurable appetite suppression and weight loss

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If bruising causes significant distress or affects treatment adherence, discussing concerns with the diabetes care team is importantalternative GLP-1 receptor agonists or delivery systems may be considered

doi: 10.1007/s11914-025-00910-9