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402,403,404 Adipose tissue hypoxia and inflammation may lead to adipocyte dysfunction and obesity-induced insulin resistance in HFD-fed models, as indicated by increased infiltration of adipose tissue macrophages (ATMs), activation of the NLRP3 inflammasome and increased levels of proinflammatory cytokines

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Characterization of the glucagon like peptide-1 receptor in male mouse brain using a novel antibody and in situ hybridization

Meanwhile, Aon found, GLP-1 use reduces cancer risk for women: Female GLP-1 users experienced a 47% reduction in hospitalizations for major cardiovascular events, approximately 50% lower incidence of ovarian cancer, and a 14% lower incidence of breast cancer, compared to female non-users, according to the analysis