Second, you can supplement NAC as seen in Figure 3
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This may help reduce oxidative stress and support healthier skin cells
However, under pathophysiological conditions, especially during APAP overdose, excessive NAPQI accumulates and binds to cellular proteins, also triggering oxidative stress, leading to hepatocellular damage and the release of damage-associated molecular patterns (DAMPs), contributing to further liver injury and inflammation
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It's commonly used in topical skincare (serums, creams) for skin rejuvenation and is also used in some injectable or wound-healing protocols