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The UK regulator recommends that in adults weighing less than 50 kg, clinical judgement should be employed when prescribing oral paracetamol as these patients may be at increased risk of hepatotoxicity but does not specify a dose reduction

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IC50 values of the 24 hit compounds in MCF-7, MDA-MB-231, and L929 cells following incubation for 72 h

PMID: 62 JacobsJPGoudarziMSinghNTongMMcHardyIHRueggerPet al