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Begin by mapping objectives, present symptoms, and background so treatment fits genuine needs rather than a cookie-cutter approach

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Importantly, the increased risks of coronary artery disease and heart failure persisted even after discontinuation, while the risks of acute coronary syndromes, stroke, and all-cause mortality were similar between early discontinuers and those who continued therapy

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[57] Ringseis R, Hanisch N, Seliger G, et al