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Clinical evidence supporting the renoprotective effects of incretin receptor agonists primarily derives from large cardiovascular outcome trials, where kidney outcomes were secondary endpoints

3jl), but outperformed GLP-1GIP to further decrease blood glucose and glucose-stimulated insulin secretion (Fig

The Prestwick chemical library, Repurposing collection, and a selection of 71 anticancer drugs, totaling 5830 compounds and including most FDA-approved small molecule drugs, were assayed, with 336 compounds identified as hits from the screening

We defined psychiatric comorbidity as having alcohol and substance abuse (ICD-10: F10-F19), schizophrenia (ICD-10: F20-F29), bipolar disorders (ICD-10: F30-F31), major depression (ICD-10: F32-F33), eating disorders (ICD-10: F50), personality disorders (ICD-10: F60-F62) and psychotropics within 10 years prior to index date ( See Supplementary Table 1)

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