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doi: 10.1093/abt/tbac028 Knox EG, Aburto MR, Clarke G, Cryan JF, ODriscoll CM
Effect of Letrozole on sperm parameters, chromatin status and ROS level in idiopathic Oligo/Astheno/Teratozoospermia
The closest human evidence in its drug class is Athira Pharma's fosgonimeton (ATH-1017), a structurally distinct molecule in the same HGF/c-Met program whose Phase 2/3 LIFT-AD Alzheimer's trial failed its primary endpoint in September 2024 (GST 0.08, P=.70)
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The Lau et al
We refer commenters to the testing results in this rule, as well as the results calculated using the July 2023 Overall Star Rating as reported in the CY 2025 OPPS/ASC final rule with comment period (89 FR 94514 through 94521) which produced similar findings
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