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Adult patients with T2DM treated by metformin, thiazolidinediones/rosiglitazone or both without adequate glycaemic control after 3 months were enrolled in SUSTAIN 2 trial to explore the comparative effectiveness of semaglutide against sitagliptin
A Danish study examining 424,152 persons with type 2 diabetes found patients exposed to weekly semaglutide had 2.19 times higher NAION risk, with Denmarks annual first-time NAION cases rising from 67.6 to 148 since Ozempics 2018 introduction
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