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Further, a screening for oxidative stress markers in patients with Parkinson's disease reported lower levels of CoQ 10 and -tocopherol and higher levels of lipoprotein oxidation in the plasma and cerebrospinal fluid compared to non-affected individuals (Buhmann et al., 10 deficiency was observed at a higher frequency in Parkinson's disease, underscoring its utility as a peripheral biomarker (Mischley et al., 2012)

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