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(Source 1) The body makes glutathione from the amino acids cysteine, glycine, and glutamine

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Major Antioxidant: Synthesis and Mechanisms of Action Timbrell, 2009, lists the three principle mechanisms of detoxification with glutathione: 1) Conjugation chemical reaction with glutathione 2) Conjugation catalysed by GSH transferase enzymes 3) Reduction by the donation of a hydrogen atom or proton as a result of oxidation of GSH

doi:10.1111/jocd.16473