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This compound has been shown to normalize H 2 S overproduction mediated by CBS, to restore normal mitochondrial function in Down syndrome [213] and to inhibit proliferation, angiogenesis and cell bioenergetics in cancer cells [214,215]

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This dual-focus strategy not only emphasizes the significance of managing uremic toxins but also highlights the necessity of personalized interventions to better protect CKD patients from cardiovascular complications

doi: 10.1080/23328940.2020.1765950 324 WaldeckerM.KautenburgerT.DaumannH.BuschC.SchrenkD