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Isoniazid (the hydrazide derivative of isonicotinic acid) was, at one time, a primary drug for chemotherapeutic treatment of tuberculosis but is now used in a cocktail of four antibiotics referred to as RIPE therapy (rifampin, isoniazid, pyrazinamide, and ethambutol)
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doi: 10.1007/s00289-016-1902-1
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