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In order to compensate for the lack of key nutrients necessary for the proper functioning of the body and fill the gap between diet and health in children with DS, dietary supplements can be used, but their usage should be controlled and in accordance with the identified deficiencies in the body

(see Table 6 in the supplementary data for a summary of the evidence) [6, 16, 82,83,84]

Retatrutide, by activating GLP-1, GIP, and glucagon receptors, may provide faster and more significant weight loss, along with enhanced fat metabolism, giving it a broader metabolic effect compared to semaglutide

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