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ESG has a longer timeframe to achieve results, over five years, while semaglutide is often used for a maximum of two
GLP-1 receptor agonist medications (including semaglutide, dulaglutide, liraglutide, exenatide, and lixisenatide) are typically considered for type 2 diabetes when: Triple therapy with other diabetes medications is not effective, not tolerated, or contraindicated The person has a BMI 35 kg/m (adjusted by 2.5 kg/m for people from South Asian, Chinese, other Asian, Black African, or African-Caribbean backgrounds) and specific weight-related psychological or medical problems A lower BMI threshold may be appropriate if weight loss would benefit other obesity-related comorbidities Insulin would not be appropriate or acceptable to the person Treatment is usually continued only if there is a beneficial metabolic response (reduction in HbA1c and weight) after 6 months
They can assess whether the insomnia is directly related to Semaglutide use or if there are other contributing factors
New or worsening symptoms could be a sign that your body is reacting to the medication in a way that needs to be addressed
On August 27, 2025, the Administrative Law Judge granted the FTCs motion and lifted the stay