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Studied as a multi-peptide reference system for how angiogenic, anti-inflammatory, and tissue-repair pathways interact in shared assays

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Because these compounds are naturally occurring peptides with restricted patentability, opportunities for intellectual property protection and industry-sponsored development are limitedposing substantial barriers to the resource-intensive clinical investigations required to confirm therapeutic efficacy and long-term safety

Additional research continues to explore its role in vascularization, collagen remodeling, and coordinated cellular response mechanisms

Collagen Production Several studies referenced by the review article showed GHK-Cu increased collagen synthesis and glycosaminoglycan production