[PubMed ID: 36290771]
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Chronic neuroinflammation has been reported to contribute to serotonergic, dopaminergic, and noradrenergic dysfunction in the brain (Song and Wang, 2011) and to lead to chronic immune dysregulation ( Figure 2 Previous studies found that pro-inflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin (IL)-6, IL-1, and C-reactive protein (CRP), are markedly increased in the blood and CSF of patients with depression (Hestad et al., 2016
The biological rationale for this category - and the one the brand leans on - is that L-Arginine and L-Citrulline serve as substrates for endothelial nitric oxide synthase (eNOS), the enzyme that produces nitric oxide in vascular tissue
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Abnormal glucose metabolism and metabolic syndrome in non-diabetic kidney transplant recipients early after transplantation