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[PubMed: 11167921] 47

doi: 10.1177/01410768221093551 210

Kessing LV

The SURPASS-3 study was started to study the efficacy and safety of TZP versus basal insulin degludec in diabetic patients inadequately controlled by metformin with or without an SGLT2-i for 52 weeks (7274)

Today, theyre widely prescribed for weight loss, cardiovascular risk reduction, and emerging indications such as sleep apnea, PCOS, and non-alcoholic fatty liver disease (NAFLD)

Additionally, research suggests that people are more likely to lose weight if the drug is taken long-term