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Conclusion What patients describe as GLP-1related food noise reflects real neuroendocrine changes that recalibrate hunger and reward signaling

Drugs of abuse drive dopamine release in the same circuit

Jean-Pierre Raufman, who made frequent trips from Brooklyn to the Bronx VA lab carrying test tubes in his Toyota Camry, the team isolated a peptide molecule they named exendin-4

Treat it as a cautious experiment with clear goals and monitoring rather than a guaranteed solution

Choosing one over another depends on your goals

Even after surgical clearance, many patients continue rotating between thighs, arms, and abdomen to distribute injection burden across multiple sites