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Amelioration of degenerative phenotypes in park 13 dopaminergic neurons Oxidative stress is one of the major underlying causes of sporadic and familial forms of Parkinsons disease and mainly characterized by an imbalanced GSH/GSSG cycle, enhancing cellular susceptibility to oxidation 37
Anitschkow NNC
Intratumoral siRNA delivery has been shown to effectively inhibit tumor growth in mouse models of cervical cancer 33
[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Dickerson EB, Akhtar N, Steinberg H, et al
In addition, it has been shown that SAG pretreatment significantly prevents CCl4-induced cytotoxicity, is protective in restoring mitochondrial autophagy, and attenuates fibrosis, collagen deposition, hepatocellular damage and organ dysfunction