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The role of ER stress and UPR in NDDs The UPR is a critical cellular mechanism activated in response to the accumulation of misfolded or unfolded proteins in the ER

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Non-immunogenic , meaning they are unlikely to trigger allergic or inflammatory reactions

6.2.2.3 EGFR-TKI resistance Halofuginone (HF), a natural product, exhibits potential in reversing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance

[ 177 Lu-DOTA 0 Tyr 3 ]octreotate: comparison with [ 111 In-DTPA 0 ]octreotide in patients