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In high-fat diet-induced obese mice, curcumin treatment led to an increase in secondary bile acids, including deoxycholic acid and lithocholic acid, which activate TGR5 receptors and promote thermogenesis, thereby ameliorating obesity [93]

doi:10.14744/SEMB.2019.59455 Kellogg TA, Bantle JP, Leslie DB, et al

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Semaglutide has become one of the most widely prescribed medications for weight loss, and for good reason