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Targeted activation of Nrf2 inhibits ROS production, thereby suppressing the proliferation and migration of fibroblast-like synovial cells, which resemble fibroblasts in rheumatoid arthritis [156]

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10.1039/d3fo03223j Food Funct

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ACSL4 catalyzes the esterification of free AA and AdA with coenzyme A (CoA) to form PUFA-CoA derivatives (AA-CoA or AdA-CoA) (Liu et al., 2022a)

Compared to the PBS-treated control group, the D-CuP-treated group exhibited 74 differentially expressed proteins (DEPs), consisting of 29 upregulated and 45 downregulated proteins (p 1.2) (Fig