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Medications: Certain medications related to bone marrow may interact with B12 shots

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High doses of vitamin C injections seem to have few side effects

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IRS recruitment activates phosphoinositide 3-kinase (PI3K), which phosphorylates PIP2 to PIP3, recruiting Akt/PKB to the membrane for activation by PDK1 this PI3K/Akt arm drives protein synthesis via mTORC1, glucose uptake via GLUT4 translocation, and cell survival via BAD phosphorylation

Meheux CJ, et al